Standard name
Human Ortholog
Description Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase; dicyclohexylcarbodiimide binding subunit; required for vacuolar acidification and important for copper and iron metal ion homeostasis

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0.07 0.11 0.16 0 0 0.99
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0.14 0.16 0.18 0 0 0
Cytoplasm 0.29 0.97 0.98 0.95 0.88 0.78 0.81 0.64 0.75 0.71 0.69 0.68 0.63 0.64 0 0.84 0
Endoplasmic Reticulum 0.79 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.08 0 0 0
Mitochondria 0 0.05 0.05 0.12 0.23 0.4 0.31 0.52 0.41 0.5 0.51 0 0 0 0 0.09 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.08 0.1 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 0 0 0 1 0 0 0 0 0 14 20 27 0 2 0
Bud 0 0 0 1 4 12 11 7 2 13 14 4 7 2 1 0 0
Bud Neck 0 0 0 1 8 8 7 7 3 6 2 0 0 0 0 1 0
Bud Site 0 0 0 0 0 0 1 0 2 3 4 0 0 0
Cell Periphery 3 2 1 2 0 3 1 0 1 2 1 29 30 30 0 1 0
Cytoplasm 51 166 219 338 287 442 412 203 321 291 415 139 120 107 3 143 0
Endoplasmic Reticulum 139 0 0 0 2 0 0 2 0 0 0 7 4 1 164 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 3 1 0 1 1 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 9 12 13 0 0 0
Mitochondria 0 8 11 44 75 225 159 167 177 204 309 2 2 0 0 15 0
Nucleus 1 0 1 1 0 1 5 0 0 0 0 0 0 0 1 0 0
Nuclear Periphery 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 2 5 12 7 17 8 10 21 1 0 0 0 1 0
Vac/Vac Membrane 0 0 0 0 0 0 0 2 2 3 0 17 19 5 3 1 0
Unique Cell Count 175 171 223 356 326 566 511 319 429 410 603 204 190 167 179 170 1
Labelled Cell Count 196 176 233 390 381 705 604 405 516 532 766 226 215 185 179 170 1


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 26.0 3.0 3.1 3.0 2.7 2.3 2.6 2.4 2.3 2.3 2.4 20.7 23.4 26.2
Std Deviation (1e-4) 6.3 0.4 1.5 1.0 1.0 0.4 0.8 0.4 0.4 0.3 0.9 5.4 6.3 6.4
Intensity Change (Log2) 0.05 -0.01 -0.13 -0.4 -0.19 -0.34 -0.37 -0.39 -0.32 2.79 2.97 3.13


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 3.5 4.4 5.5
Bud 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 4.6 4.9 5.3
Cytoplasm 0.7 -1.1 -3.4 -5.7 -5.2 -8.2 -6.3 -7.0 -7.5 -7.2 -7.9 -7.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 3.3 3.7
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 3.9 4.2 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration
Actin
Bud
Bud Neck
Bud Periphery
Bud Site
Cell Periphery
Cytoplasm
Cytoplasmic Foci
Eisosomes
Endoplasmic Reticulum
Endosome
Golgi
Lipid Particles
Mitochondria
None
Nuclear Periphery
Nucleolus
Nucleus
Peroxisomes
Punctate Nuclear
Vacuole
Vacuole Periphery

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 871.5296 927.1528 1148.6661 899.2611 922.6411 723.7796 866.722 859.1769 1011.9065 803.421
Translational Efficiency 1.5457 1.4656 1.3282 1.7285 1.5496 2.0603 1.9364 1.7745 1.5933 1.7428

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vma3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available