| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 4 |
| Bud | 0 | 0 | 0 | 0 | 1 | 0 | 4 | 3 | 2 | 2 | – | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 9 | 1 | 1 | 8 | 1 |
| Bud Neck | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 5 | 4 | 0 | – | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 1 | 1 | 4 | 2 |
| Bud Site | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
| Cell Periphery | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 1 |
| Cytoplasm | 47 | 149 | 81 | 22 | 90 | 122 | 144 | 110 | 74 | 79 | – | 17 | 186 | 194 | 198 | 259 | 192 | 136 | 23 | 69 | 30 | 25 | 70 | 59 |
| Endoplasmic Reticulum | 0 | 2 | 0 | 0 | 1 | 2 | 0 | 2 | 3 | 0 | – | 0 | 1 | 2 | 2 | 17 | 16 | 10 | 0 | 0 | 1 | 1 | 2 | 4 |
| Endosome | 0 | 2 | 0 | 0 | 0 | 4 | 3 | 5 | 0 | 0 | – | 0 | 0 | 1 | 0 | 19 | 13 | 4 | 8 | 6 | 2 | 3 | 4 | 6 |
| Golgi | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 4 | 0 | 0 | 1 | 1 |
| Mitochondria | 10 | 2 | 0 | 0 | 0 | 11 | 14 | 8 | 13 | 31 | – | 9 | 0 | 2 | 1 | 5 | 1 | 2 | 5 | 6 | 7 | 3 | 6 | 5 |
| Nucleus | 2 | 3 | 2 | 2 | 3 | 9 | 18 | 19 | 14 | 7 | – | 1 | 0 | 0 | 0 | 21 | 19 | 22 | 0 | 1 | 0 | 1 | 1 | 0 |
| Nuclear Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | – | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Nucleolus | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | – | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| SpindlePole | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | – | 0 | 0 | 0 | 0 | 1 | 4 | 1 | 4 | 5 | 3 | 1 | 6 | 2 |
| Vac/Vac Membrane | 5 | 30 | 3 | 4 | 24 | 29 | 44 | 28 | 17 | 18 | – | 4 | 2 | 0 | 0 | 100 | 102 | 74 | 50 | 95 | 40 | 31 | 84 | 57 |
| Unique Cell Count | 59 | 181 | 85 | 26 | 112 | 168 | 206 | 165 | 111 | 116 | 26 | 189 | 197 | 201 | 359 | 286 | 217 | 100 | 212 | 99 | 75 | 196 | 158 | |
| Labelled Cell Count | 64 | 190 | 87 | 28 | 121 | 179 | 232 | 183 | 131 | 137 | 32 | 189 | 201 | 203 | 427 | 349 | 251 | 100 | 212 | 99 | 75 | 196 | 158 | |
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 3.5 | 4.8 | 6.1 | 5.9 | 5.5 | 4.8 | 4.6 | 5.0 | 4.2 | 4.0 | – | 3.8 | 4.6 | 4.2 | 4.3 | 5.5 | 6.0 | 6.6 | 4.3 | 5.0 | 6.0 |
| Std Deviation (1e-4) | 0.4 | 1.2 | 1.9 | 4.0 | 1.8 | 1.9 | 1.3 | 1.7 | 1.0 | 1.2 | – | 0.5 | 1.5 | 1.5 | 1.8 | 1.6 | 1.6 | 2.2 | 1.3 | 2.1 | 2.5 |
| Intensity Change (Log2) | – | – | – | -0.05 | -0.17 | -0.36 | -0.41 | -0.28 | -0.56 | -0.61 | – | -0.69 | -0.42 | -0.54 | -0.5 | -0.14 | -0.03 | 0.11 | -0.51 | -0.3 | -0.02 |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | 0 | 0 | 0 |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | 4.8 | 5.8 | 5.5 |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasmic Foci | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Eisosomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Lipid Particles | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| None | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Punctate Nuclear | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 13.8857 | 7.2661 | 16.1753 | 70.3168 | 93.0908 | 6.0928 | 9.1835 | 10.7436 | 30.5208 | 129.0647 |
| Translational Efficiency | 0.3086 | 0.6969 | 0.5334 | 0.8296 | 1.2271 | 1.4095 | 0.5833 | 0.619 | 1.3682 | 1.2784 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | – |
| Gene Expression | ✔ |
| Translational Efficiency | ✘ |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p |
| Localization | |
| Cell Percentages | cytoplasm (15%), vacuole (10%), mixed (50%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | N/A |
Scw11
Scw11
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Scw11-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
