Standard name
Human Ortholog
Description Protein involved in cell separation during budding; one of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; SDS23 has a paralog, SDS24, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 1.0 0.98 0.98 0.96 0.85 0.85 0.76 0.75 0.74 0.75 1.0 1.0 0.99 0.98 0.99 0.98 0.97 0.98 0.93 0.89 0.95 0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0.06 0.05 0.16 0.15 0.17 0.21 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.06 0.07 0.05 0.05 0.06 0.07 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3
Bud 0 0 1 0 0 0 3 4 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 4 1 2 2 5 13 10 9 15 5 7 1 3 1 10 8 3 0 0 0 0 0 0
Cytoplasm 143 244 248 198 290 305 480 415 238 254 131 154 97 226 204 418 278 179 138 239 229 67 162 143
Endoplasmic Reticulum 0 2 0 0 2 3 18 18 13 18 4 9 0 0 1 11 9 1 0 0 4 2 1 3
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Golgi 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 0 0 0 0 0 1 0
Mitochondria 1 0 1 1 0 8 35 25 49 51 30 44 0 0 0 2 0 1 0 0 1 0 0 1
Nucleus 0 1 1 1 1 4 7 10 6 4 4 4 0 0 0 3 2 4 0 1 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 1 1 0 0 0 1 1 0 0 1 0 0 0 0 0 0 1 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 4 4 5 31 33 16 17 10 14 0 1 0 4 0 2 0 3 2 0 0 0
Unique Cell Count 144 246 249 202 296 318 562 490 313 338 178 206 97 226 206 428 280 182 143 245 246 75 171 159
Labelled Cell Count 145 251 252 206 299 332 590 516 333 363 185 236 98 230 207 450 298 190 143 245 246 75 171 159


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 15.4 19.0 17.6 15.9 14.2 11.7 10.1 10.7 10.3 9.4 9.4 9.1 15.0 16.7 15.9 18.9 22.1 23.7 14.8 15.9 16.7
Std Deviation (1e-4) 2.5 2.4 3.0 3.1 2.3 2.6 2.2 2.1 2.6 2.1 2.8 2.2 3.1 2.3 2.3 4.7 5.0 5.6 2.6 2.5 3.6
Intensity Change (Log2) – – – -0.15 -0.32 -0.59 -0.8 -0.72 -0.78 -0.9 -0.91 -0.95 -0.23 -0.08 -0.15 0.1 0.33 0.42 -0.25 -0.15 -0.08


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 3.0 0 0 0 0 0 0 0 0
Cytoplasm -1.6 -1.7 -2.8 -6.1 -6.3 -8.1 -8.3 -8.4 -8.2 0.6 1.0 -0.7 -1.9 -0.5 -1.3
Endoplasmic Reticulum 0 0 0 2.9 3.1 3.3 3.7 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 3.7 3.3 6.3 6.2 6.5 7.5 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 3.8 4.2 3.6 3.6 0 4.2 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.8925 14.8602 12.2901 11.9653 11.5014 12.8079 11.4985 15.5638 13.7566 12.4043 11.6918 13.3396 14.9164 18.1046 14.7212 14.876 14.9557 15.8009
Actin 0.0397 0.0004 0.016 0.0002 0.0009 0.0078 0.0183 0.0005 0.0054 0.0025 0.0422 0.0065 0.0206 0.0003 0.019 0.0024 0.0005 0.0088
Bud 0.0005 0.0001 0.0005 0.0001 0.0001 0.0002 0.0006 0 0.0003 0.0049 0.0026 0.0006 0.0011 0 0.0014 0.0003 0 0.0001
Bud Neck 0.0017 0.0003 0.0009 0.0006 0.0006 0.0011 0.0008 0.0001 0.0006 0.0005 0.0025 0.0008 0.0005 0.0001 0.0083 0.0007 0.0006 0.0014
Bud Periphery 0.0007 0 0.0007 0 0.0001 0.0002 0.0006 0 0.0002 0.0058 0.0024 0.0007 0.0018 0 0.0008 0.0001 0 0.0001
Bud Site 0.0039 0.0002 0.0006 0.0001 0.0003 0.0007 0.0008 0.0001 0.0013 0.0297 0.0021 0.0008 0.0051 0.0001 0.0017 0.0008 0 0.0001
Cell Periphery 0.0003 0 0.0002 0.0001 0.0001 0 0.0002 0 0.0001 0.0008 0.0002 0.0001 0.0004 0 0.0001 0 0 0
Cytoplasm 0.7981 0.9937 0.9256 0.9916 0.8582 0.976 0.8111 0.9966 0.9425 0.8822 0.8223 0.9157 0.8681 0.9961 0.8723 0.9447 0.9265 0.9697
Cytoplasmic Foci 0.0206 0.0003 0.0089 0.0006 0.0047 0.0011 0.0328 0.0007 0.0147 0.0134 0.0188 0.0095 0.0148 0.0003 0.0313 0.0325 0.0066 0.0029
Eisosomes 0.0004 0 0.0001 0 0.0001 0.0001 0.0002 0 0 0 0.0001 0.0001 0.0003 0 0.0001 0 0 0
Endoplasmic Reticulum 0.005 0.0004 0.0008 0.0012 0.0009 0.001 0.0123 0.0001 0.0016 0.0068 0.0146 0.0033 0.0071 0.0002 0.0012 0.0006 0.0003 0.0016
Endosome 0.0235 0.0001 0.0017 0.0005 0.0067 0.0008 0.0416 0 0.0122 0.0318 0.0457 0.0161 0.0244 0 0.0122 0.0043 0.0007 0.0035
Golgi 0.0078 0 0.0012 0 0.0029 0.0008 0.0108 0 0.003 0.0036 0.0149 0.011 0.005 0 0.0082 0.0015 0.0016 0.001
Lipid Particles 0.0277 0 0.0022 0 0.0427 0.0003 0.0051 0 0.0011 0.0021 0.0024 0.0025 0.0136 0 0.0063 0.0014 0.0082 0.0003
Mitochondria 0.0163 0 0.0065 0.0001 0.0644 0.0018 0.003 0 0.0026 0.0015 0.0136 0.0187 0.0125 0 0.0038 0.0003 0.0006 0.0003
None 0.005 0.0002 0.0005 0.0003 0.0003 0.0003 0.031 0.0004 0.0013 0.0034 0.0017 0.0008 0.0039 0.0002 0.0023 0.0017 0.0003 0.0014
Nuclear Periphery 0.0077 0.0007 0.004 0.0009 0.0015 0.001 0.012 0.0001 0.0043 0.0027 0.004 0.0039 0.005 0.0003 0.0019 0.0006 0.0004 0.0011
Nucleolus 0.0013 0 0.0002 0 0.0004 0 0.0003 0 0.0001 0.0001 0.0001 0 0.0009 0 0.0002 0.0001 0 0
Nucleus 0.0091 0.0034 0.0104 0.0024 0.0043 0.0058 0.0076 0.0012 0.0044 0.0034 0.0031 0.0046 0.0065 0.0023 0.0038 0.0038 0.0044 0.0063
Peroxisomes 0.0221 0 0.0155 0 0.0074 0.0004 0.0009 0 0.0022 0.0004 0.0021 0.0022 0.0013 0 0.016 0.0017 0.049 0.0001
Punctate Nuclear 0.0045 0.0001 0.0004 0.0001 0.0006 0.0001 0.0039 0.0001 0.0009 0.001 0.0008 0.0006 0.0014 0 0.0085 0.0021 0.0002 0.0005
Vacuole 0.0029 0.0002 0.0024 0.001 0.0018 0.0004 0.005 0 0.001 0.0026 0.0028 0.0008 0.0039 0 0.0004 0.0003 0.0001 0.0005
Vacuole Periphery 0.0011 0 0.0006 0.0002 0.001 0.0001 0.0015 0 0.0003 0.0007 0.001 0.0005 0.0018 0 0.0002 0.0001 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 26.8189 27.3993 30.4972 31.573 25.7402 20.8862 35.2589 25.0723 22.9586 35.6271
Translational Efficiency 1.5769 1.4768 1.3153 0.9735 1.2644 1.9705 1.1327 1.5112 1.628 1.1326

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sds23-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available