Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L24B; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24B has a paralog, RPL24A, that arose from the whole genome duplication

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0.05 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0.06 0.05 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.99 1.0 0.96 0.88 0.66 0.69 0.68 0.7 0.65 0.99 0.99 0.97 0.99 0.98 0.99 0.97 0.94 0.93 0.94 0.95 0.91
Endoplasmic Reticulum 0 0 0 0 0 0.09 0.3 0.23 0.26 0.2 0.26 0 0 0 0 0 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0.08 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 4 17 31 32 25 28 0 0 0 0 0 0 0 0 0 0 0 0
Bud 1 0 5 0 0 1 4 7 3 2 2 1 1 8 0 1 0 4 0 3 1 4 11
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Cell Periphery 3 0 3 0 6 14 21 40 38 25 28 1 1 5 3 0 0 0 0 1 0 0 0
Cytoplasm 680 209 382 411 609 515 445 471 519 320 345 469 440 547 282 183 178 655 186 356 214 353 356
Endoplasmic Reticulum 2 0 3 2 26 54 203 157 196 90 137 6 4 13 11 7 12 1 1 9 3 3 4
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 2 0 0 0 0 2 8 32 18 9 16 0 0 0 1 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 1 23 12 39 33 0 0 0 0 0 1 0 0 2 0 0 0
Nucleus 0 0 0 0 1 1 1 2 1 1 4 0 1 0 0 0 0 2 1 1 1 1 4
Nuclear Periphery 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 1 0 5 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 2 0 0 0 2 10 1 8 1 0 1 0 2 0 2 1 1 1 1 4 3 7
Unique Cell Count 685 211 384 413 636 582 679 682 761 459 532 475 443 564 286 187 180 673 198 383 227 373 392
Labelled Cell Count 688 211 393 413 643 594 715 765 827 514 594 478 447 575 297 193 192 673 198 383 227 373 392


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 134.9 174.6 74.1 96.1 78.9 56.8 46.5 41.7 39.1 36.2 36.2 129.8 141.6 140.3 206.5 134.0 195.9 134.4 142.5 139.0
Std Deviation (1e-4) 30.7 31.3 19.3 22.1 15.9 13.1 10.4 9.7 9.2 8.7 8.7 29.9 31.8 26.3 67.2 52.0 70.1 34.9 39.3 45.6
Intensity Change (Log2) 0.37 0.09 -0.38 -0.67 -0.83 -0.92 -1.04 -1.03 0.81 0.93 0.92 1.48 0.85 1.4 0.86 0.94 0.91


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 3.1 4.2 4.1 4.6 4.6 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0.2 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 1.9 2.4 4.1 3.6 3.8 3.7 0 0 0 0 0 0
Cytoplasm 0.1 -3.5 -6.5 -12.8 -11.9 -12.2 -11.5 -12.8 -1.1 -0.3 -2.7 -1.2 -1.8 -0.8
Endoplasmic Reticulum 0 3.1 5.5 11.5 9.8 10.5 8.7 10.4 0 0 1.8 2.7 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 4.3 3.0 0 3.4 0 0 0 0 0 0
Mitochondria 0 0 0 0 3.6 0 5.8 5.0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 134.1725 165.2924 151.9413 146.6067 115.3978 149.3322 131.1885 166.9607 153.5211 135.9964 123.4401 141.3138 144.726 184.199 167.4091 164.0737 144.4536 78.2623
Actin 0.0082 0.0008 0.002 0.0007 0.0125 0.0008 0.0106 0.0006 0.0014 0.0077 0.0107 0.0072 0.0021 0.0002 0.0004 0.0005 0.0007 0.0012
Bud 0.0016 0.001 0.0014 0.0017 0.001 0.0007 0.0019 0.0007 0.0012 0.0018 0.0013 0.002 0.0021 0.0004 0.0018 0.0023 0.0012 0.0084
Bud Neck 0.0011 0.0005 0.0008 0.0005 0.0038 0.0009 0.0021 0.0005 0.0008 0.0022 0.0005 0.0023 0.0005 0.0003 0.0007 0.001 0.0023 0.0015
Bud Periphery 0.0025 0.0006 0.001 0.0006 0.0009 0.0003 0.0041 0.0004 0.0009 0.0013 0.0009 0.0026 0.0024 0.0002 0.0022 0.0011 0.0007 0.0044
Bud Site 0.0007 0.0007 0.0013 0.0002 0.0012 0.0001 0.0041 0.0004 0.0008 0.0026 0.0008 0.0003 0.0009 0.0005 0.0005 0.0003 0.0007 0.0007
Cell Periphery 0.0225 0.012 0.0168 0.0099 0.0013 0.0076 0.0346 0.0167 0.0278 0.0087 0.0048 0.0161 0.0469 0.0128 0.0177 0.0197 0.0306 0.0069
Cytoplasm 0.6434 0.9017 0.8189 0.62 0.7189 0.7566 0.6715 0.9105 0.7765 0.6518 0.689 0.6705 0.6781 0.9196 0.8501 0.6556 0.7414 0.4701
Cytoplasmic Foci 0.0019 0.0013 0.0111 0.0029 0.0349 0.0035 0.0132 0.0011 0.0079 0.0187 0.0157 0.011 0.0105 0.0033 0.0039 0.0018 0.0269 0.0817
Eisosomes 0.0004 0 0.0001 0 0.0002 0 0.0005 0.0001 0.0009 0.0001 0.0009 0.0001 0.0016 0 0 0 0 0.0006
Endoplasmic Reticulum 0.0606 0.0143 0.0273 0.0022 0.0086 0.0485 0.0517 0.0102 0.0072 0.0081 0.0041 0.0755 0.0296 0.0153 0.0047 0.0023 0.0053 0.0041
Endosome 0.0109 0.0026 0.0089 0.0121 0.0256 0.0096 0.0125 0.002 0.0075 0.0155 0.0112 0.0321 0.0062 0.0012 0.0044 0.006 0.0125 0.0082
Golgi 0.0017 0.0005 0.0016 0.0008 0.0064 0.0014 0.0045 0.0006 0.0031 0.0102 0.0134 0.0278 0.0016 0.0007 0.0011 0.0002 0.0047 0.0012
Lipid Particles 0.0019 0.0007 0.0031 0.0008 0.013 0.0006 0.006 0.0024 0.0045 0.0129 0.0094 0.0034 0.007 0.0005 0.0036 0.0005 0.0041 0.0156
Mitochondria 0.0104 0.001 0.0042 0.0007 0.0034 0.001 0.0098 0.0012 0.0085 0.0083 0.0453 0.0064 0.0086 0.0005 0.0085 0.0005 0.0011 0.024
None 0.003 0.0004 0.0019 0.0004 0.0079 0.0004 0.0069 0.0002 0.0048 0.0008 0.026 0.0032 0.0079 0.0011 0.001 0.0003 0.0007 0.0454
Nuclear Periphery 0.0539 0.0043 0.0083 0.0057 0.0129 0.0562 0.0213 0.0031 0.0065 0.0062 0.0039 0.021 0.0308 0.0025 0.0049 0.0098 0.0069 0.0089
Nucleolus 0.0027 0.0004 0.0007 0.0005 0.0011 0.0003 0.0073 0.0003 0.0025 0.0013 0.02 0.0037 0.0056 0.0008 0.0033 0.0008 0.0074 0.0292
Nucleus 0.014 0.0023 0.0039 0.0039 0.0047 0.005 0.008 0.0016 0.0039 0.0054 0.0056 0.0284 0.0081 0.0017 0.0045 0.0081 0.0331 0.0188
Peroxisomes 0.0006 0.0001 0.0023 0.0001 0.013 0.0001 0.0028 0 0.0014 0.0225 0.003 0.0002 0.0033 0 0.0015 0.0001 0.0157 0.0022
Punctate Nuclear 0.0005 0 0.0019 0 0.0295 0.0001 0.0026 0 0.0005 0.0009 0.0003 0.0003 0.0005 0.0001 0.0001 0 0.0006 0.0049
Vacuole 0.1167 0.0475 0.0647 0.263 0.0665 0.0785 0.1052 0.0421 0.1141 0.1587 0.0965 0.0614 0.1249 0.0358 0.0741 0.2297 0.09 0.1522
Vacuole Periphery 0.041 0.0072 0.0179 0.0735 0.0326 0.0279 0.0188 0.0052 0.017 0.0541 0.0367 0.0244 0.0209 0.0025 0.0109 0.0591 0.0135 0.1097

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1615.0257 1814.6792 2306.8423 1615.6471 2066.4397 1908.6812 1545.5324 1459.1598 1882.2134 1401.7576
Translational Efficiency 1.6996 1.6206 1.3558 2.1777 1.7406 1.3575 1.4889 1.9081 1.3399 1.793

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L24B; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24B has a paralog, RPL24A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-1

Rpl24b

Rpl24b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl24b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available