Standard name
Human Ortholog
Description Subunit VIII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.12 0 0 0.07
Bud 0 0 0 0.06 0 0
Bud Neck 0 0 0 0 0 0
Bud Site 0 0 0 0
Cell Periphery 0 0.08 0.1 0.06 0 0
Cytoplasm 0 0 0.08 0.06 0 0
Endoplasmic Reticulum 0 0 0 0.11 0 0
Endosome 0 0 0 0.11 0.14 0.05
Golgi 0 0 0.34 0.17 0.07 0.11
Mitochondria 0.93 0.91 0.08 0.17 0.6 0.61
Nucleus 0 0 0 0.06 0 0
Nuclear Periphery 0 0 0.06 0 0 0
Nucleolus 0 0 0 0.06 0 0
Peroxisomes 0 0.07 0.12 0.17 0.07 0.07
SpindlePole 0 0 0.08 0.06 0 0
Vac/Vac Membrane 0.09 0.12 0.2 0.17 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 6 0 8 14
Bud 9 1 1 1 2 1
Bud Neck 0 0 0 0 2 0
Bud Site 1 0 2 0
Cell Periphery 5 16 5 1 0 2
Cytoplasm 5 2 4 1 0 2
Endoplasmic Reticulum 4 3 0 2 0 1
Endosome 8 3 0 2 50 10
Golgi 1 8 17 3 24 21
Mitochondria 302 173 4 3 218 124
Nucleus 2 0 0 1 0 0
Nuclear Periphery 4 6 3 0 3 2
Nucleolus 2 3 1 1 1 0
Peroxisomes 13 14 6 3 24 14
SpindlePole 6 0 4 1 4 0
Vac/Vac Membrane 28 23 10 3 13 4
Unique Cell Count 326 191 50 18 362 204
Labelled Cell Count 390 253 63 22 362 204


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 8.1 10.6 8.9
Std Deviation (1e-4) 0.8 1.7 3.7 2.4
Intensity Change (Log2)


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin
Bud
Bud Neck
Bud Site
Cell Periphery
Cyto
Endoplasmic Reticulum
Endosome
Golgi
Mitochondria
Nuclear Periphery
Nuc
Nucleolus
Peroxisomes
SpindlePole
Vac
Cortical Patches
Cytoplasm
Nucleus
Vacuole

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration
Actin
Bud
Bud Neck
Bud Periphery
Bud Site
Cell Periphery
Cytoplasm
Cytoplasmic Foci
Eisosomes
Endoplasmic Reticulum
Endosome
Golgi
Lipid Particles
Mitochondria
None
Nuclear Periphery
Nucleolus
Nucleus
Peroxisomes
Punctate Nuclear
Vacuole
Vacuole Periphery

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 46.5571 24.9715 46.3249 78.4265 57.3452 37.2251 42.0812 62.4843 46.7006 63.3654
Translational Efficiency 3.3339 5.849 2.9755 1.4869 3.4819 5.1387 3.6747 2.2505 3.9063 2.7105

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency
Standard name
Human Ortholog
Description Subunit VIII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain
Localization
Cell Percentages mitochondrion (94%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Cox8

Cox8


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cox8-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available