Standard name | |
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Human Ortholog | |
Description | Glucose-repressible alcohol dehydrogenase II; catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1 |
ensLOC | DeepLoc | |||||||||||||||||||||||
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Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
Cortical Patches | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 2 | 0 | 2 | 1 | 1 | 1 |
Bud | 1 | 1 | 2 | 0 | 2 | 1 | 2 | 3 | 5 | 3 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2 |
Bud Neck | 0 | 0 | 3 | 1 | 7 | 3 | 6 | 13 | 8 | 7 | 0 | 5 | 2 | 4 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Bud Site | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | – | – | – | – | – | – |
Cell Periphery | 0 | 0 | 1 | 1 | 2 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 4 | 0 | 1 | 5 | 6 | 2 | 0 | 2 | 1 | 2 | 1 |
Cytoplasm | 183 | 55 | 98 | 102 | 194 | 210 | 258 | 282 | 214 | 181 | 124 | 98 | 194 | 165 | 195 | 125 | 157 | 157 | 136 | 75 | 65 | 96 | 198 | 190 |
Endoplasmic Reticulum | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3 | 6 | 11 | 5 | 0 | 0 | 1 | 1 | 0 |
Endosome | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Golgi | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Mitochondria | 11 | 6 | 0 | 4 | 0 | 11 | 45 | 42 | 81 | 44 | 46 | 56 | 0 | 0 | 0 | 2 | 3 | 3 | 23 | 10 | 16 | 5 | 11 | 7 |
Nucleus | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 3 | 0 | 3 | 3 | 1 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nuclear Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nucleolus | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peroxisomes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SpindlePole | 0 | 0 | 0 | 2 | 1 | 1 | 3 | 11 | 1 | 1 | 5 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 2 | 1 |
Vac/Vac Membrane | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 7 | 3 | 2 | 1 | 2 | 1 | 0 | 1 |
Unique Cell Count | 189 | 60 | 101 | 103 | 197 | 218 | 277 | 318 | 252 | 213 | 156 | 134 | 196 | 166 | 195 | 128 | 166 | 164 | 186 | 94 | 100 | 114 | 223 | 214 |
Labelled Cell Count | 196 | 64 | 106 | 110 | 207 | 232 | 317 | 358 | 313 | 244 | 181 | 168 | 199 | 174 | 196 | 135 | 185 | 184 | 186 | 94 | 100 | 114 | 223 | 214 |
Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean Cell GFP Intensity (1e-4) | 2.9 | 3.7 | 4.2 | 4.1 | 4.8 | 3.9 | 3.3 | 4.9 | 3.1 | 3.1 | 3.0 | 3.2 | 4.4 | 4.8 | 4.9 | 5.9 | 6.1 | 6.0 | 4.2 | 4.5 | 4.6 |
Std Deviation (1e-4) | 0.5 | 0.5 | 1.4 | 1.8 | 2.1 | 2.2 | 1.8 | 12.7 | 1.5 | 0.8 | 1.4 | 1.3 | 1.3 | 1.3 | 1.5 | 1.6 | 2.1 | 2.4 | 1.6 | 1.4 | 1.4 |
Intensity Change (Log2) | – | – | – | -0.01 | 0.21 | -0.09 | -0.32 | 0.22 | -0.44 | -0.45 | -0.48 | -0.4 | 0.09 | 0.2 | 0.22 | 0.49 | 0.54 | 0.52 | -0.0 | 0.11 | 0.15 |
Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cyto | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nuc | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
SpindlePole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Vac | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cortical Patches | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
R1 | R2 | R3 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Concentration | -0.0556 | 0.1672 | -0.1188 | -0.2541 | -0.5854 | -0.2876 | -0.9041 | -0.3992 | -0.5748 | -0.873 | 0.8031 | -0.5482 | -1.4845 | -1.4982 | -1.8088 | -1.2709 | -1.3793 | -1.4134 |
Actin | 0.0072 | 0.0006 | 0.0136 | 0.0018 | 0.005 | 0.0013 | 0.0382 | 0.0005 | 0.0169 | 0.0006 | 0.067 | 0.0051 | 0.0255 | 0.001 | 0.0027 | 0.0051 | 0.0022 | 0.0043 |
Bud | 0.001 | 0.0016 | 0.0006 | 0.0001 | 0.0005 | 0.0003 | 0.0006 | 0.0019 | 0.0029 | 0.0005 | 0.0022 | 0.0039 | 0.0042 | 0.0002 | 0.0031 | 0.0001 | 0.0002 | 0.0015 |
Bud Neck | 0.0024 | 0.0002 | 0.001 | 0.0004 | 0.0001 | 0.0007 | 0.0006 | 0.0003 | 0.004 | 0.0004 | 0.002 | 0.0007 | 0.0068 | 0 | 0.0002 | 0.0001 | 0.0002 | 0.0007 |
Bud Periphery | 0.0021 | 0.0031 | 0.0017 | 0.0001 | 0.002 | 0.0006 | 0.001 | 0.0072 | 0.0129 | 0.0016 | 0.0056 | 0.007 | 0.0096 | 0.0002 | 0.003 | 0.0002 | 0.0002 | 0.0044 |
Bud Site | 0.006 | 0.0032 | 0.0055 | 0.0005 | 0.0001 | 0.0004 | 0.004 | 0.0038 | 0.0036 | 0.0005 | 0.0046 | 0.0008 | 0.0235 | 0.0003 | 0.0043 | 0.0003 | 0.0015 | 0.0003 |
Cell Periphery | 0.0005 | 0.0002 | 0.0002 | 0.0001 | 0 | 0.0001 | 0.0003 | 0.0002 | 0.0005 | 0 | 0.0004 | 0.0003 | 0.0009 | 0.0001 | 0.0001 | 0.0001 | 0 | 0.0002 |
Cytoplasm | 0.0852 | 0.1318 | 0.099 | 0.0849 | 0.2097 | 0.0999 | 0.0479 | 0.0313 | 0.049 | 0.0982 | 0.0505 | 0.1118 | 0.0929 | 0.1594 | 0.16 | 0.0369 | 0.1461 | 0.1827 |
Cytoplasmic Foci | 0.0347 | 0.0189 | 0.0182 | 0.008 | 0.0537 | 0.013 | 0.0073 | 0.0045 | 0.0078 | 0.0426 | 0.015 | 0.0156 | 0.0363 | 0.0078 | 0.0157 | 0.005 | 0.0337 | 0.0412 |
Eisosomes | 0.0004 | 0.0002 | 0.0003 | 0.0001 | 0.0002 | 0.0001 | 0.0006 | 0.0002 | 0.0006 | 0.0001 | 0.001 | 0.0001 | 0.0007 | 0.0002 | 0.0004 | 0.0002 | 0.0001 | 0.0001 |
Endoplasmic Reticulum | 0.0034 | 0.0011 | 0.0007 | 0.0004 | 0.0015 | 0.0005 | 0.0021 | 0.0003 | 0.006 | 0.001 | 0.0119 | 0.0012 | 0.0027 | 0.0013 | 0.0009 | 0.0008 | 0.0016 | 0.0021 |
Endosome | 0.0431 | 0.0067 | 0.0129 | 0.0319 | 0.0585 | 0.011 | 0.0191 | 0.0003 | 0.0105 | 0.0144 | 0.0453 | 0.0045 | 0.0224 | 0.0038 | 0.0046 | 0.0466 | 0.0045 | 0.0344 |
Golgi | 0.0142 | 0.002 | 0.0072 | 0.0105 | 0.0271 | 0.0077 | 0.006 | 0.0001 | 0.0034 | 0.0045 | 0.0109 | 0.0033 | 0.0094 | 0.0017 | 0.0023 | 0.0036 | 0.004 | 0.0226 |
Lipid Particles | 0.0186 | 0.0017 | 0.0063 | 0.0079 | 0.0154 | 0.0075 | 0.0069 | 0.0003 | 0.0029 | 0.0195 | 0.0145 | 0.0067 | 0.0248 | 0.0004 | 0.0007 | 0.0019 | 0.1025 | 0.0132 |
Mitochondria | 0.0143 | 0.0019 | 0.0059 | 0.0185 | 0.0051 | 0.0072 | 0.0132 | 0.0042 | 0.016 | 0.002 | 0.0127 | 0.0034 | 0.0172 | 0.0019 | 0.003 | 0.1061 | 0.0069 | 0.0332 |
None | 0.7277 | 0.8224 | 0.8078 | 0.8063 | 0.6015 | 0.8386 | 0.8133 | 0.9304 | 0.831 | 0.7895 | 0.6122 | 0.819 | 0.6762 | 0.8183 | 0.7749 | 0.7788 | 0.6267 | 0.6398 |
Nuclear Periphery | 0.0031 | 0.0002 | 0.0004 | 0.0002 | 0.0009 | 0.0004 | 0.0152 | 0.0006 | 0.0114 | 0.001 | 0.0867 | 0.0009 | 0.0015 | 0.0004 | 0.0032 | 0.0005 | 0.0002 | 0.0013 |
Nucleolus | 0.003 | 0.0002 | 0.0016 | 0.0009 | 0.0001 | 0.0005 | 0.002 | 0.001 | 0.0007 | 0.0004 | 0.0008 | 0.0009 | 0.0061 | 0.0001 | 0.0003 | 0.0002 | 0.0002 | 0.0005 |
Nucleus | 0.0023 | 0.0005 | 0.0015 | 0.0005 | 0.002 | 0.001 | 0.0052 | 0.0019 | 0.0046 | 0.0009 | 0.0072 | 0.0014 | 0.004 | 0.001 | 0.0099 | 0.0004 | 0.0003 | 0.0007 |
Peroxisomes | 0.0204 | 0.002 | 0.013 | 0.0094 | 0.0142 | 0.007 | 0.0042 | 0.0007 | 0.0075 | 0.0193 | 0.0318 | 0.0099 | 0.0194 | 0.0005 | 0.003 | 0.0064 | 0.0676 | 0.0078 |
Punctate Nuclear | 0.0044 | 0.0009 | 0.0014 | 0.0004 | 0.0011 | 0.0009 | 0.008 | 0.0096 | 0.0035 | 0.0018 | 0.0106 | 0.0016 | 0.0072 | 0.0003 | 0.0012 | 0.0004 | 0.0008 | 0.0061 |
Vacuole | 0.0046 | 0.0006 | 0.0009 | 0.0151 | 0.0009 | 0.0012 | 0.002 | 0.0004 | 0.0025 | 0.0008 | 0.0032 | 0.0013 | 0.0078 | 0.0008 | 0.0035 | 0.0047 | 0.0003 | 0.0016 |
Vacuole Periphery | 0.0013 | 0.0001 | 0.0002 | 0.002 | 0.0003 | 0.0002 | 0.0021 | 0.0001 | 0.0018 | 0.0003 | 0.004 | 0.0005 | 0.0008 | 0.0001 | 0.0029 | 0.0015 | 0.0001 | 0.0015 |
R1 | R2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
Gene Expression | 1208.7917 | 1367.9257 | 1752.5862 | 1039.9303 | 1314.4688 | 1377.702 | 1365.7242 | 1458.1192 | 1968.2566 | 1129.4909 |
Translational Efficiency | 0.9855 | 0.9631 | 0.7783 | 1.5838 | 1.0603 | 0.9885 | 1.203 | 1.1855 | 0.8545 | 1.2223 |
Dataset | Hit |
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Protein Concentration | ✘ |
Protein Localization | ✘ |
Gene Expression | ✘ |
Translational Efficiency | ✘ |
Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
---|---|---|---|---|
37℃ | ||||
RT |
Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
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Gene | Images |
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Gene | Images |
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