Standard name
Human Ortholog
Description Histone H3; core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT1); regulated by acetylation, methylation, and phosphorylation; H3K14 acetylation plays an important role in the unfolding of strongly positioned nucleosomes during repair of UV damage
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Cytoplasm 0.93 0.95 0.95 0.91 0.9 0.86 – 0.85 0.6 0.69 0.74 0.51 0.99 0.94 0.98 0.89 0.8 0.95 0.76 0.82 0.69 0.8 0.77 0.73
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.06 0.16 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.1 0.07 0 0.2 0.07 0.23 – 0.21 0.64 0.5 0.41 0.66 0 0.05 0 0.06 0 0 0 0.07 0.1 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.08 0 0 0.05 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1
Bud 0 0 0 0 0 0 – 2 1 2 0 2 0 0 0 1 0 0 1 0 0 0 2 3
Bud Neck 0 0 0 0 0 0 – 1 1 3 0 0 0 0 0 1 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 – 1 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 1 1 1 0 – 1 1 0 0 0 0 0 0 1 0 2 0 0 1 0 0 0
Cytoplasm 38 57 53 50 77 63 – 129 82 93 56 64 85 60 64 62 20 38 49 72 59 43 71 82
Endoplasmic Reticulum 0 0 1 1 0 0 – 0 1 0 0 0 0 0 0 4 4 2 0 0 0 0 0 0
Endosome 0 0 0 0 1 1 – 2 0 0 1 0 0 0 1 1 1 1 0 0 2 1 1 2
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1
Mitochondria 4 4 2 11 6 17 – 32 87 67 31 82 0 3 0 4 1 1 2 6 8 0 3 4
Nucleus 0 1 0 0 3 1 – 0 0 1 0 1 1 1 0 1 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 0
Nucleolus 1 0 0 2 2 1 – 3 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 2 0 – 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 3 1 3 0 4 0 0 0 0 0 0 2 0 2 0 1 2
Vac/Vac Membrane 0 0 2 0 1 2 – 3 4 3 1 2 0 0 0 2 2 1 1 4 3 1 4 6
Unique Cell Count 41 60 56 55 86 73 152 137 135 76 125 86 64 65 70 25 40 65 89 87 54 93 113
Labelled Cell Count 43 63 59 65 93 85 179 180 172 90 156 87 64 65 78 29 45 65 89 87 54 93 113


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.4 4.0 4.3 5.6 6.8 4.3 – 5.3 3.0 3.8 3.9 3.3 4.9 4.4 4.8 5.1 5.8 6.1 4.0 5.4 6.3
Std Deviation (1e-4) 0.6 0.8 3.0 4.6 5.1 3.7 – 4.8 2.2 2.8 3.4 3.2 2.2 1.5 2.5 1.2 2.2 2.4 1.2 3.0 4.1
Intensity Change (Log2) – – – 0.39 0.66 -0.01 – 0.3 -0.51 -0.18 -0.13 -0.36 0.19 0.04 0.17 0.25 0.44 0.5 -0.1 0.33 0.55


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.544 -0.3882 -0.1959 -0.0449 -0.0412 -0.283 2.0669 -1.0396 -0.9508 -0.4228 -0.9215 -0.5637 6.6829 0.115 0.4513 0.4478 -0.0538 0.4487
Actin 0.0873 0.0028 0.0213 0.0075 0.0998 0.0087 0.1346 0.0004 0.0006 0.0281 0.0046 0.0236 0.2769 0.0013 0.0021 0.0103 0 0.004
Bud 0.0013 0.0014 0.001 0.0073 0.0139 0.0002 0.0014 0.002 0.0002 0.0009 0.0003 0.0002 0.0019 0.0024 0.0008 0.0002 0 0.002
Bud Neck 0.0988 0.0003 0.0013 0.0027 0.0015 0.0007 0.0016 0.0001 0.0131 0.0258 0.0001 0.0008 0.0019 0.0001 0.0002 0.0001 0 0.0032
Bud Periphery 0.0017 0.0028 0.0025 0.0279 0.0353 0.0002 0.0016 0.004 0.0003 0.0024 0.0003 0.0005 0.0018 0.0042 0.0032 0.0003 0 0.0037
Bud Site 0.0322 0.0103 0.0059 0.012 0.0275 0.0007 0.0085 0.0012 0.0008 0.0055 0.0008 0.0003 0.0145 0.0018 0.0145 0.0004 0 0.0034
Cell Periphery 0.0022 0.0002 0.0002 0.0006 0.0016 0.0001 0.0006 0.0001 0.0002 0.0009 0 0.0002 0.0005 0.0001 0.0006 0 0 0.0004
Cytoplasm 0.0173 0.0549 0.0537 0.0197 0.0678 0.0808 0.1213 0.0877 0.0717 0.0892 0.0939 0.1191 0.1038 0.0387 0.0315 0.0443 0.1058 0.1275
Cytoplasmic Foci 0.1517 0.0045 0.0128 0.0478 0.0134 0.0398 0.0994 0.0057 0.0164 0.0167 0.0394 0.0092 0.0729 0.0053 0.0047 0.0085 0.0035 0.0098
Eisosomes 0.0029 0.0001 0.0001 0.0001 0.0006 0.0001 0.0021 0.0002 0.0001 0.0006 0 0.0002 0.0008 0.0001 0.0002 0.0002 0 0.0001
Endoplasmic Reticulum 0.0047 0.0003 0.0028 0.0007 0.0076 0.0006 0.0124 0.0008 0.0004 0.0014 0.0002 0.0051 0.0127 0.0002 0.0008 0.0003 0.0002 0.0013
Endosome 0.0744 0.0029 0.0103 0.028 0.034 0.014 0.145 0.0021 0.0075 0.0257 0.0126 0.025 0.0529 0.0012 0.0211 0.0194 0.0008 0.0079
Golgi 0.0265 0.0019 0.0031 0.0289 0.0401 0.017 0.0771 0.0005 0.0043 0.0108 0.0093 0.0068 0.0361 0.0015 0.0049 0.0291 0 0.0049
Lipid Particles 0.0427 0.0027 0.0033 0.0221 0.0112 0.013 0.0354 0.0009 0.0015 0.003 0.008 0.0094 0.0289 0.0005 0.0035 0.0036 0 0.0037
Mitochondria 0.0152 0.0098 0.0051 0.0148 0.0463 0.0075 0.0204 0.0027 0.0162 0.0825 0.0021 0.0094 0.0108 0.0003 0.0027 0.1016 0.0001 0.0008
None 0.288 0.9015 0.8656 0.7323 0.5369 0.7961 0.2577 0.8871 0.8637 0.6945 0.7679 0.7665 0.2276 0.94 0.9055 0.7679 0.8888 0.8188
Nuclear Periphery 0.0177 0.0002 0.0018 0.0018 0.0112 0.0006 0.0098 0.0005 0.0002 0.0008 0.0001 0.0013 0.0612 0.0001 0.0003 0.0001 0.0001 0.0005
Nucleolus 0.0051 0.0001 0.0004 0.0006 0.005 0.0002 0.0011 0.0004 0.0004 0.0003 0.0001 0.0004 0.0008 0 0.0001 0 0 0.0001
Nucleus 0.0101 0.0002 0.0006 0.0008 0.0111 0.0004 0.0027 0.0005 0.0003 0.0006 0.0002 0.0008 0.0067 0.0001 0.0003 0.0001 0.0001 0.0008
Peroxisomes 0.0494 0.0019 0.0035 0.0255 0.0045 0.0155 0.028 0.001 0.0006 0.0046 0.0476 0.0111 0.0638 0.0017 0.0006 0.0129 0 0.005
Punctate Nuclear 0.0446 0.0002 0.0013 0.0023 0.0022 0.0025 0.0174 0.0007 0.0005 0.0036 0.0007 0.0007 0.0164 0.0001 0.0002 0.0001 0 0.0007
Vacuole 0.0202 0.0007 0.003 0.0155 0.0232 0.0006 0.0158 0.0013 0.0008 0.0016 0.0108 0.0081 0.0039 0.0002 0.0018 0.0003 0.0004 0.0012
Vacuole Periphery 0.006 0.0001 0.0002 0.0011 0.0051 0.0006 0.0062 0.0002 0.0002 0.0006 0.0009 0.0018 0.0031 0 0.0004 0.0003 0.0001 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1496.7104 995.9759 236.8545 253.2548 1613.3545 802.2756 773.472 542.1043 458.6573 1227.4875
Translational Efficiency 1.7031 1.8019 1.4704 1.4807 1.4851 3.0789 1.7731 1.596 1.5726 2.0292

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Hht2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available