Standard name
Human Ortholog
Description Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity and in microtubule assembly
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 1.0 0.99 0.95 0.95 0.79 0.72 0.73 – 0.65 0.67 0.63 0.98 0.98 0.98 0.94 0.92 0.98 0.92 0.95 0.96 0.95 0.95 0.91
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.07 0.25 0.28 0.29 – 0.31 0.34 0.37 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.05 0 0.06 0.11 0.12 – 0.13 0.11 0.11 0 0 0 0 0.08 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 10 3 3 – 3 6 20 2 1 0 0 0 0 0 1 0 0 1 2
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 1 1 4 3 – 5 6 9 2 1 2 2 1 0 0 0 0 0 0 0
Cytoplasm 124 289 246 230 309 311 315 285 – 262 289 329 318 424 445 107 98 50 136 282 245 218 269 270
Endoplasmic Reticulum 0 2 1 0 2 2 3 0 – 2 1 2 1 4 4 2 6 1 0 1 4 0 0 1
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 1 0 0 0 1 0 0 1 0 3
Golgi 2 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 1 1 0 1 0 0
Mitochondria 1 0 4 4 22 99 122 114 – 126 146 193 0 0 0 2 2 0 2 1 1 1 1 2
Nucleus 1 0 0 0 3 7 5 8 – 19 10 17 5 4 3 4 0 1 0 3 0 1 2 1
Nuclear Periphery 1 0 0 0 0 3 1 3 – 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 0 0 1 0 – 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 3 0 0 12 9 23 49 46 – 53 47 55 4 0 7 5 8 2 2 0 0 3 6 11
Unique Cell Count 128 290 249 243 325 394 435 393 405 429 523 323 431 452 114 106 51 148 297 256 229 284 297
Labelled Cell Count 132 291 252 247 346 456 503 462 471 508 629 332 434 462 122 116 54 148 297 256 229 284 297


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.8 9.8 6.6 7.2 6.4 5.9 5.4 5.7 – 5.3 5.5 5.4 10.2 10.2 10.2 11.8 11.8 12.2 10.7 11.0 11.2
Std Deviation (1e-4) 1.5 1.4 1.0 1.7 1.3 1.2 1.2 1.2 – 1.0 1.1 1.1 1.3 1.3 1.2 2.8 2.9 2.0 1.4 1.6 1.7
Intensity Change (Log2) – – – 0.12 -0.06 -0.16 -0.3 -0.22 – -0.32 -0.27 -0.28 0.63 0.62 0.62 0.84 0.83 0.88 0.7 0.74 0.76


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 – 0 0 3.1 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm -2.6 -2.5 -7.2 -8.6 -8.6 – -10.2 -9.7 -10.7 -0.3 -0.4 -0.4 -2.7 -3.2 -0.4
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 0 2.9 7.9 8.6 8.7 – 9.2 9.8 10.5 0 0 0 0 0 0
Nucleus 0 0 0 0 0 – 3.5 0 2.9 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 3.6 0 3.9 5.5 5.6 – 6.0 5.4 5.3 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.9642 6.6723 6.0154 4.8509 5.551 6.0344 6.9626 9.4047 7.9524 7.5435 7.0102 7.9919 6.0427 7.9265 6.8891 6.6134 6.7656 6.851
Actin 0.0285 0.0003 0.002 0.0578 0.037 0.0058 0.0079 0.0019 0.0102 0.0011 0.0004 0.0074 0.0002 0.0001 0.0002 0.0001 0.0002 0.0006
Bud 0.0003 0.0001 0.0015 0.0003 0.0004 0.0001 0.0003 0.0042 0.0063 0.0003 0.0001 0.001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0005
Bud Neck 0.0007 0.0001 0.0003 0.0015 0.0012 0.0013 0.0015 0.0002 0.0004 0.0005 0.0002 0.0008 0.0002 0.0002 0.0003 0.0003 0.0005 0.0008
Bud Periphery 0.0002 0 0.0004 0.0004 0.0005 0 0.0002 0.001 0.0041 0.0001 0 0.0005 0 0 0 0 0 0.0002
Bud Site 0.0006 0.0002 0.0022 0.002 0.0006 0.0002 0.0014 0.0041 0.0011 0.0003 0.0001 0.0002 0.0001 0.0002 0.0001 0.0001 0.0001 0
Cell Periphery 0 0 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0001 0 0 0 0 0 0 0 0 0
Cytoplasm 0.8712 0.9764 0.9429 0.8128 0.8802 0.93 0.8777 0.9649 0.9189 0.9107 0.8982 0.9487 0.9615 0.9811 0.9702 0.969 0.9673 0.9497
Cytoplasmic Foci 0.0092 0.0013 0.0057 0.0051 0.0085 0.0038 0.0203 0.0035 0.0117 0.0572 0.0667 0.0052 0.0031 0.0016 0.002 0.0022 0.0063 0.0047
Eisosomes 0.0005 0 0 0.0014 0.0005 0.0001 0 0 0.0001 0 0 0.0005 0 0 0 0 0 0
Endoplasmic Reticulum 0.0058 0.0008 0.0018 0.001 0.0026 0.0037 0.0077 0.0011 0.0023 0.0017 0.0014 0.0016 0.0023 0.0007 0.0011 0.0019 0.0009 0.0015
Endosome 0.0174 0.0004 0.0021 0.0025 0.0064 0.0034 0.0193 0.0006 0.0087 0.0026 0.0066 0.0019 0.0018 0.0005 0.0006 0.0024 0.0021 0.0016
Golgi 0.0033 0 0.0004 0.0034 0.0036 0.0009 0.0033 0.0001 0.0025 0.0006 0.001 0.0009 0.0001 0 0 0 0.0001 0.0001
Lipid Particles 0.0026 0 0.0016 0.0138 0.002 0.0017 0.0029 0.0001 0.0032 0.0018 0.0069 0.0004 0 0 0 0 0 0
Mitochondria 0.0012 0.0001 0.0005 0.0222 0.0014 0.0003 0.0007 0.0007 0.002 0.0002 0.0001 0.0037 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
None 0.0243 0.0093 0.0097 0.0144 0.0088 0.0102 0.0254 0.0083 0.0141 0.0062 0.002 0.0125 0.01 0.0025 0.0037 0.0034 0.0074 0.0047
Nuclear Periphery 0.0091 0.0011 0.0019 0.0015 0.0075 0.0051 0.0039 0.0012 0.002 0.0013 0.0009 0.0016 0.0023 0.001 0.0013 0.0016 0.0009 0.002
Nucleolus 0.0003 0 0.0002 0.0002 0.0003 0.0001 0.0002 0.0003 0.0002 0 0 0 0 0 0 0 0 0
Nucleus 0.0144 0.0092 0.0139 0.0246 0.0163 0.0298 0.0151 0.0055 0.0068 0.0077 0.0041 0.0111 0.0168 0.0113 0.0194 0.0175 0.0127 0.0304
Peroxisomes 0.0025 0 0.0084 0.0335 0.0003 0.0004 0.0024 0.0002 0.003 0.0048 0.0063 0.0004 0 0 0.0001 0 0.0001 0.0001
Punctate Nuclear 0.0062 0.0003 0.0041 0.0008 0.0202 0.0022 0.0082 0.0016 0.0015 0.0028 0.0047 0.001 0.0007 0.0004 0.0005 0.0004 0.0007 0.0023
Vacuole 0.0012 0.0002 0.0005 0.0004 0.0009 0.0007 0.0011 0.0003 0.0006 0.0003 0.0002 0.0004 0.0006 0.0002 0.0002 0.0008 0.0004 0.0005
Vacuole Periphery 0.0005 0 0.0001 0.0002 0.0006 0.0002 0.0003 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0 0 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 44.7841 27.2574 34.1316 37.752 46.9458 49.521 37.8949 42.4337 51.2789 43.8702
Translational Efficiency 1.5078 2.1586 1.3531 1.4414 1.195 1.2662 1.2858 1.1525 0.9935 1.1752

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rho2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available