Standard name
Human Ortholog
Description Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.39 0.33 0.31 0.13 0.3 0.15 0.11 0.08 0.1 0.07 0.07 0 0.29 0.19 0.07 0.11 – – 0.44 0.4 0.42 0.31 0.35 0.23
Bud 0.07 0.11 0.19 0.11 0.19 0.12 0.13 0.08 0.07 0.08 0.1 0.08 0.12 0.07 0.09 0.08 – – 0.06 0.07 0.05 0.06 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0.13 0.18 0.12 0.15 0.12 0.14
Bud Site 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – – –
Cell Periphery 0.39 0.3 0.2 0.18 0.14 0.17 0.13 0.14 0.17 0.19 0.16 0.17 0.46 0.47 0.39 0.15 – – 0.22 0.15 0.17 0.19 0.24 0.25
Cytoplasm 0.37 0.45 0.54 0.67 0.52 0.6 0.53 0.56 0.51 0.5 0.49 0.57 0.49 0.64 0.8 0.53 – – 0.05 0.09 0.08 0.13 0.13 0.15
Endoplasmic Reticulum 0 0.09 0 0 0.11 0 0.07 0.06 0.09 0.05 0.05 0 0.07 0.07 0 0.08 – – 0.06 0 0.05 0.07 0.05 0.09
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Mitochondria 0 0 0.06 0.16 0.09 0.28 0.34 0.28 0.37 0.41 0.45 0.35 0 0 0 0.09 – – 0 0 0.07 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.08 0 0.06 0.06 0.13 0 0 0 0 – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 152 94 132 36 99 62 56 48 32 29 27 26 40 41 19 6 – – 213 136 214 47 86 56
Bud 28 31 80 30 64 49 67 44 23 37 43 46 16 15 23 4 – – 30 24 22 9 10 7
Bud Neck 0 0 4 0 4 0 0 0 0 1 2 0 0 0 0 0 – – 63 60 59 23 29 33
Bud Site 7 12 20 10 5 10 3 8 6 5 2 3 2 1 3 2 – – – – – – – –
Cell Periphery 151 85 86 49 46 70 64 80 58 81 64 100 64 101 103 8 – – 105 52 85 29 60 60
Cytoplasm 142 126 229 180 173 245 267 322 173 219 203 343 67 137 211 28 – – 23 31 39 19 32 36
Endoplasmic Reticulum 15 26 12 5 35 17 36 35 29 23 20 11 10 14 5 4 – – 26 13 23 9 12 22
Endosome 2 6 1 2 0 3 2 2 0 0 1 3 0 0 4 2 – – 0 2 5 0 3 4
Golgi 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 – – 4 3 1 2 0 2
Mitochondria 2 10 24 44 29 114 169 157 124 181 186 209 1 2 1 5 – – 11 3 33 3 3 5
Nucleus 6 0 2 0 0 2 2 4 0 1 2 4 1 4 1 1 – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 1 2 3 3 3 0 4 5 0 1 0 0 – – 1 0 0 0 0 0
Nucleolus 0 1 0 1 0 0 0 1 0 0 0 0 0 0 0 2 – – 0 0 0 0 0 0
Peroxisomes 8 4 1 2 0 0 0 2 0 0 0 0 1 0 1 1 – – 0 0 0 0 0 0
SpindlePole 17 7 11 2 3 2 1 1 1 3 2 4 3 4 2 6 – – 0 1 1 2 1 4
Vac/Vac Membrane 13 4 1 3 2 8 14 47 9 26 24 77 0 0 1 1 – – 2 5 10 2 2 3
Unique Cell Count 385 283 422 268 333 405 502 570 336 437 412 602 138 213 263 53 487 338 506 153 246 243
Labelled Cell Count 544 407 603 364 461 584 684 754 458 606 580 831 205 320 374 72 487 338 506 153 246 243


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.8 7.5 5.1 5.1 5.4 5.3 5.1 5.6 5.0 5.0 5.0 5.1 7.8 8.3 7.0 11.1 – – 7.8 8.3 8.9
Std Deviation (1e-4) 1.4 1.6 0.8 1.0 0.9 1.0 1.1 1.4 1.2 1.2 1.4 1.3 1.1 1.6 1.2 2.6 – – 1.7 1.7 1.8
Intensity Change (Log2) – – – -0.0 0.07 0.06 -0.0 0.14 -0.03 -0.03 -0.04 -0.01 0.6 0.69 0.46 1.11 – – 0.61 0.69 0.8


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -5.3 -0.5 -5.4 -7.6 -9.2 -7.2 -9.3 -9.1 -11.8 -0.5 -3.2 -7.4 -3.0 – –
Bud -2.7 0.1 -2.7 -2.3 -5.3 -4.8 -4.5 -3.5 -5.4 -2.0 -4.0 -3.6 -2.1 – –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Bud Site -0.6 -2.5 -1.7 -4.0 -3.1 -2.2 -3.1 -3.8 -4.5 -1.7 -2.8 -2.5 0 – –
Cell Periphery -0.7 -2.4 -1.1 -3.1 -2.6 -1.1 -0.7 -1.8 -1.5 6.0 7.1 5.3 -0.9 – –
Cytoplasm 3.4 -0.6 1.8 -0.3 0.7 -0.8 -1.2 -1.4 0.9 -1.2 2.4 6.9 -0.2 – –
Endoplasmic Reticulum -0.8 4.3 1.1 3.0 2.4 3.5 1.8 1.5 -1.1 2.3 2.2 -0.8 0 – –
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Mitochondria 4.6 1.6 8.7 10.4 8.8 10.8 12.3 13.1 10.9 -2.5 -2.9 -3.6 0 – –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 – –
SpindlePole -1.8 -1.7 -2.4 -3.2 -3.5 -2.5 -2.2 -2.5 -2.5 0 -0.6 0 0 – –
Vacuole 0 0 0 3.1 5.8 0 4.8 4.7 7.5 0 0 0 0 – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.5087 5.3897 5.3552 5.337 5.8207 5.5317 6.6326 6.4511 6.6016 6.6103 6.4807 6.4176 8.0227 7.0038 6.7521 6.4672 7.5281 6.4225
Actin 0.1733 0.1412 0.2753 0.3117 0.1934 0.2191 0.1285 0.0466 0.2125 0.24 0.3182 0.1201 0.1706 0.0452 0.2785 0.2074 0.279 0.1521
Bud 0.0035 0.0089 0.0172 0.026 0.0169 0.0059 0.0036 0.006 0.0157 0.0348 0.0151 0.0052 0.0018 0.0066 0.0192 0.0177 0.0134 0.0043
Bud Neck 0.0407 0.0122 0.066 0.0616 0.0392 0.1298 0.0243 0.0124 0.0708 0.0482 0.0086 0.1569 0.0247 0.0269 0.0684 0.0351 0.0433 0.1416
Bud Periphery 0.0207 0.0305 0.1155 0.2662 0.2054 0.0554 0.0169 0.0188 0.112 0.3095 0.1673 0.0459 0.0133 0.0257 0.1386 0.1484 0.1491 0.0363
Bud Site 0.0649 0.3256 0.1037 0.0213 0.0104 0.013 0.0716 0.39 0.2302 0.016 0.0117 0.0097 0.1032 0.4038 0.1944 0.0285 0.0122 0.0123
Cell Periphery 0.2788 0.0945 0.1241 0.0851 0.1337 0.1631 0.2057 0.1007 0.0987 0.0862 0.1068 0.1643 0.3565 0.0699 0.0873 0.1261 0.1825 0.1763
Cytoplasm 0.3305 0.3577 0.2522 0.1875 0.3529 0.3785 0.3373 0.4026 0.1823 0.1786 0.2863 0.4616 0.2424 0.415 0.0974 0.2855 0.2906 0.4257
Cytoplasmic Foci 0.0052 0.0039 0.0018 0.0047 0.0019 0.0026 0.022 0.002 0.0066 0.0091 0.0018 0.0037 0.0041 0.001 0.0212 0.0209 0.0051 0.0098
Eisosomes 0.0134 0.0042 0.0043 0.0053 0.002 0.0031 0.0144 0.0011 0.0019 0.0009 0.0018 0.003 0.0095 0.0009 0.0025 0.0028 0.002 0.008
Endoplasmic Reticulum 0.0282 0.0063 0.0074 0.0132 0.0256 0.015 0.0123 0.0039 0.0021 0.003 0.0142 0.0056 0.0057 0.0019 0.0025 0.0552 0.0027 0.0051
Endosome 0.0017 0.0009 0.0006 0.0007 0.0011 0.0012 0.0213 0.0004 0.0136 0.0112 0.0329 0.0031 0.0154 0.0002 0.0156 0.0103 0.0018 0.0006
Golgi 0.0072 0.0031 0.0037 0.0033 0.0027 0.007 0.0098 0.001 0.0149 0.0191 0.0044 0.003 0.005 0.0007 0.0207 0.0201 0.0123 0.0018
Lipid Particles 0.0032 0.0024 0.001 0.002 0.001 0.0017 0.0123 0.0007 0.0033 0.0048 0.0008 0.0007 0.0021 0.0002 0.0105 0.0012 0.0004 0.0048
Mitochondria 0.0005 0.0002 0.0002 0.0002 0.0007 0.0005 0.0069 0.0002 0.0238 0.0029 0.0023 0.0003 0.0015 0 0.0022 0.0102 0.0003 0.0002
None 0.0218 0.0046 0.0239 0.0083 0.004 0.0008 0.0324 0.0102 0.0037 0.0302 0.0129 0.0095 0.0022 0.0009 0.0178 0.0011 0.0033 0.0103
Nuclear Periphery 0.0011 0.0006 0.0006 0.0008 0.0019 0.0005 0.0171 0.0005 0.0003 0.0003 0.0032 0.0025 0.01 0.0002 0.0067 0.0087 0.0003 0.0002
Nucleolus 0.0004 0.0001 0.0001 0.0001 0.0001 0.0001 0.0026 0.0001 0.0003 0.0001 0.0001 0.0001 0.0022 0 0.0005 0.0002 0.0001 0.0006
Nucleus 0.0011 0.0005 0.0005 0.0004 0.0008 0.0004 0.0309 0.0005 0.0004 0.0003 0.0005 0.0024 0.0167 0.0002 0.006 0.0052 0.0004 0.0005
Peroxisomes 0.0003 0.0002 0.0001 0.0003 0.0001 0.0001 0.0142 0.0001 0.0034 0.0024 0.0001 0.0002 0.0042 0 0.0044 0.0048 0.0002 0.0069
Punctate Nuclear 0.0008 0.0002 0.0002 0.0002 0.0002 0.0002 0.0077 0.0001 0.0002 0.0001 0.0002 0.0006 0.0022 0.0001 0.0037 0.0002 0.0001 0.0007
Vacuole 0.0025 0.0019 0.0016 0.0012 0.0053 0.0017 0.0064 0.0018 0.0029 0.002 0.0053 0.0013 0.0054 0.0005 0.0016 0.0091 0.0009 0.0021
Vacuole Periphery 0.0001 0.0001 0.0001 0.0001 0.0009 0.0002 0.0019 0.0001 0.0004 0.0002 0.0055 0.0001 0.0014 0 0.0004 0.0014 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 18.6192 15.108 15.9612 28.2313 22.098 27.1977 18.8358 22.1055 29.1437 27.4885
Translational Efficiency 0.9993 0.9801 1.145 0.8377 0.8475 0.7076 0.7953 0.7378 0.7182 0.6735

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2246 873 320 867 1609 2077 419 382 3855 2950 739 1249

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 783.60 930.00 1508.25 984.01 824.68 890.16 1245.82 1127.23 800.75 901.95 1359.46 1027.81
Standard Deviation 99.35 122.23 175.89 135.57 234.00 120.68 142.08 178.76 170.34 122.50 204.33 163.97
Intensity Change Log 2 — 0.247113 0.944686 0.328556 — 0.110230 0.595189 0.450876 — 0.178547 0.776047 0.392572

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.073943 0.101704* 0.142493* 0.120113* 0.088653 0.114292* 0.216240* 0.172223* 0.080083 0.110567* 0.184306* 0.136051*
Bud Neck 0.131226 0.089113 0.074434 0.050727 0.114784 0.111563 0.085379 0.087282 0.124363 0.104919 0.080640 0.061908
Bud Site 0.223738* 0.332413* 0.197148* 0.381726* 0.188842* 0.242967* 0.350966* 0.515282* 0.209173* 0.269437* 0.284360* 0.422574*
Cell Periphery 0.092117 0.104331* 0.419315* 0.010590 0.157839* 0.127957* 0.149077* 0.106893* 0.119548* 0.120966* 0.266095* 0.040044
Cytoplasm 0.332235* 0.266594* 0.048098 0.231106* 0.272818* 0.296159* 0.083227 0.075090 0.307436* 0.287410* 0.068015 0.183390*
Cytoplasmic Foci 0.025772 0.026629 0.012490 0.052083 0.033322 0.015350 0.014511 0.003115 0.028923 0.018688 0.013636 0.037106
Eisosomes 0.049334 0.018950 0.025758 0.003417 0.049614 0.036714 0.028681 0.009392 0.049451 0.031457 0.027415 0.005244
Endoplasmic Reticulum 0.003393 0.005094 0.021254 0.001624 0.006192 0.004390 0.009725 0.002000 0.004561 0.004599 0.014717 0.001739
Endosome 0.005943 0.006768 0.003521 0.009401 0.012884 0.005115 0.002041 0.000399 0.008840 0.005604 0.002682 0.006648
Golgi 0.010854 0.013979 0.004699 0.004071 0.015301 0.008435 0.001143 0.000461 0.012710 0.010076 0.002683 0.002967
Lipid Particles 0.005836 0.002309 0.024356 0.002970 0.015814 0.002328 0.004404 0.002499 0.010001 0.002322 0.013044 0.002826
Mitochondria 0.011376 0.007317 0.000315 0.003698 0.009736 0.011786 0.000122 0.000164 0.010692 0.010464 0.000206 0.002617
Mitotic Spindle 0.000149 0.000204 0.000400 0.015047 0.000182 0.001039 0.000224 0.000972 0.000163 0.000792 0.000300 0.010742
None 0.000530 0.000062 0.000048 0.000095 0.003218 0.000188 0.000032 0.000019 0.001652 0.000151 0.000039 0.000072
Nuclear Periphery 0.000028 0.000020 0.000217 0.000070 0.000085 0.000025 0.000035 0.000016 0.000052 0.000024 0.000114 0.000054
Nuclear Periphery Foci 0.000127 0.000158 0.001160 0.000552 0.000327 0.000142 0.000920 0.000305 0.000210 0.000147 0.001024 0.000477
Nucleolus 0.000063 0.000027 0.000008 0.000270 0.000121 0.000053 0.000008 0.000005 0.000088 0.000045 0.000008 0.000189
Nucleus 0.005683 0.001681 0.001308 0.003695 0.006000 0.002935 0.003321 0.001369 0.005815 0.002564 0.002449 0.002984
Peroxisomes 0.017611 0.009726 0.001490 0.015547 0.014389 0.010846 0.002710 0.001090 0.016266 0.010515 0.002182 0.011126
Vacuole 0.009386 0.011865 0.021322 0.091957 0.008536 0.006820 0.047194 0.021389 0.009031 0.008313 0.035991 0.070375
Vacuole Periphery 0.000655 0.001057 0.000166 0.001239 0.001345 0.000893 0.000042 0.000033 0.000943 0.000941 0.000095 0.000870

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.66 -6.42 -5.29 -1.29 2.40 -4.83 -10.21 -7.12 -4.90 2.77 -8.05 -12.26 -8.06 -3.02 5.30
Bud Neck 7.19 6.62 16.23 7.27 3.06 0.58 4.01 3.73 3.46 -0.18 4.82 7.85 15.27 10.60 3.45
Bud Site -9.94 2.02 -11.33 -2.05 -10.17 -6.87 -10.27 -19.05 -15.95 -7.64 -9.71 -6.80 -19.75 -13.27 -9.21
Cell Periphery -1.76 -17.83 22.76* 15.13 22.68* 4.40 0.94 5.20 2.41 3.07 -0.31 -12.67 18.71 17.81 19.74
Cytoplasm 6.64 35.42 9.23 2.42 -18.33 -2.84 19.91 20.83 24.28 0.63 3.22 37.47 15.05 12.11 -14.60
Cytoplasmic Foci -0.29 2.50 -6.52 -5.82 -6.56 7.10 4.62 12.36 7.89 3.65 6.01 4.77 -3.17 -6.40 -6.09
Eisosomes 12.99 8.21 23.55 11.22 10.18 4.77 5.27 14.53 12.67 5.13 9.77 8.67 28.25 21.05 10.07
Endoplasmic Reticulum -1.68 -8.76 3.95 3.72 9.81 1.89 -1.89 5.01 2.96 4.28 -0.06 -7.34 6.68 5.04 9.67
Endosome -0.91 3.23 -2.92 -1.98 -5.01 5.70 8.19 9.80 9.34 4.74 4.39 8.94 2.49 -1.14 -4.96
Golgi -1.78 5.31 7.08 5.90 0.73 4.53 10.45 10.94 11.34 3.71 2.69 12.30 11.70 8.89 -0.25
Lipid Particles 6.61 -3.53 4.27 -1.05 4.07 6.85 4.98 5.64 -0.22 1.04 8.65 -1.20 7.10 -0.87 4.18
Mitochondria 3.20 14.50 5.14 2.30 -2.33 -1.58 11.92 11.85 11.42 -0.99 0.24 18.83 7.59 6.60 -2.40
Mitotic Spindle -0.91 -4.60 -4.66 -4.65 -4.60 -1.58 -0.62 -1.18 0.01 -1.10 -1.65 -2.65 -4.73 -4.43 -4.68
None 7.22 7.44 6.23 -1.59 -2.14 2.61 2.75 2.77 5.96 1.27 3.09 3.33 3.25 2.97 -2.06
Nuclear Periphery 3.07 -5.87 -2.33 -2.73 3.65 2.93 2.39 3.32 2.13 4.16 3.23 -3.70 -0.39 -2.39 2.72
Nuclear Periphery Foci -1.96 -7.50 -4.99 -4.65 3.32 2.93 -5.01 0.07 -3.23 5.18 1.88 -9.17 -4.34 -5.15 4.72
Nucleolus 9.41 19.99 -1.31 -1.50 -1.61 1.75 3.07 3.15 3.37 1.27 2.32 5.15 -0.97 -1.31 -1.60
Nucleus 11.08 11.31 1.75 -4.32 -4.69 3.41 2.38 5.11 3.51 2.78 7.04 5.89 3.79 -1.92 -1.66
Peroxisomes 5.32 16.00 1.03 -3.02 -8.66 2.92 7.66 13.23 12.39 1.31 6.16 14.44 3.77 -0.53 -6.79
Vacuole -1.97 -4.19 -14.98 -14.45 -11.76 2.15 -6.74 -3.93 -4.31 3.20 1.20 -7.68 -15.13 -15.26 -6.95
Vacuole Periphery -2.28 7.28 -1.14 -0.29 -2.16 2.29 7.77 7.81 8.09 0.97 0.02 10.60 0.28 0.27 -2.25
Standard name
Human Ortholog
Description Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (18%), cell periphery (9%), mixed (44%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Osh2

Osh2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Osh2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available