Standard name
Human Ortholog
Description Essential component of the Arp2/3 complex; Arp2/3 is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity; required for efficient Golgi-to-ER trafficking in COPI mutants
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.05 0 0.09 0 0.06 0.1 0 0 0 0.08 0.1 0.12 0.2 0.07 0.08 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.19 0.31 0.06 0 0.09 0.56 0.47 0.34 0.58 0.54 0.69 0.51 0.07 0 0 0.08 0.06 0.06 0 0 0 0 0 0
Nucleus 0.94 0.85 0.91 0.94 0.84 0.7 0.69 0.68 0.64 0.61 0.57 0.59 0.84 0.87 0.77 0.84 0.87 0.87 0.89 0.81 0.74 0.67 0.62 0.61
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0.06 0 0 0 0.05 0.05 0.06 0 0.06 0.06 0.05 0 0 0 0 0 0 0 0.05 0.13 0.12 0.13 0.14
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0.08 0.12 0.1
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1 0 1 0
Bud 0 2 0 1 1 9 25 8 19 19 14 10 1 0 0 0 0 0 3 6 2 2 2 2
Bud Neck 0 0 1 0 1 1 1 2 0 0 0 1 0 0 0 0 1 0 0 1 1 0 2 3
Bud Site 0 1 0 3 4 14 12 11 25 26 25 19 0 0 0 0 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3 14 29 16 49 30 63 83 29 25 27 52 21 28 43 13 14 17 1 8 0 2 2 2
Endoplasmic Reticulum 0 1 1 0 0 0 0 0 0 0 0 1 3 0 1 4 4 6 0 0 3 3 1 2
Endosome 0 1 4 3 8 0 2 11 2 6 1 10 1 1 3 3 2 3 0 4 9 2 6 9
Golgi 0 0 3 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 3 1 2 0
Mitochondria 56 147 36 14 52 428 457 295 455 452 514 342 14 2 1 15 10 14 0 5 3 5 6 12
Nucleus 277 409 528 419 476 528 674 591 506 513 424 394 179 200 167 149 155 216 271 407 446 146 166 212
Nuclear Periphery 0 0 8 2 0 3 6 3 3 4 2 8 0 0 0 0 0 3 0 1 3 0 0 0
Nucleolus 9 29 26 10 16 35 50 51 30 49 41 31 5 1 2 5 3 7 10 25 78 26 33 48
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0
SpindlePole 3 2 4 3 15 3 12 28 13 11 7 16 8 5 3 2 3 11 3 9 6 6 7 9
Vac/Vac Membrane 1 3 1 3 11 18 12 18 17 27 19 26 2 1 2 7 6 4 10 26 34 17 32 36
Unique Cell Count 296 481 581 447 570 759 970 868 786 844 744 670 212 231 217 178 179 247 304 504 602 219 269 348
Labelled Cell Count 349 609 641 474 634 1069 1314 1101 1099 1132 1074 910 235 239 223 199 198 282 304 504 602 219 269 348


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 4.7 5.4 5.2 5.1 3.7 4.0 4.4 3.9 3.9 3.7 3.7 5.7 5.9 6.0 6.3 6.2 6.0 5.4 5.6 5.9
Std Deviation (1e-4) 0.6 0.9 1.4 1.2 2.1 1.1 1.7 1.5 1.3 0.9 0.9 1.1 1.1 1.0 1.2 1.1 1.2 1.0 1.1 1.2 1.0
Intensity Change (Log2) – – – -0.06 -0.08 -0.58 -0.43 -0.31 -0.49 -0.46 -0.56 -0.55 0.07 0.12 0.14 0.21 0.2 0.14 -0.01 0.05 0.11


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin – – – – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – – – – –
Bud Periphery – – – – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – – – – –
Cytoplasmic Foci – – – – – – – – – – – – – – – – – –
Eisosomes – – – – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – – – – –
Lipid Particles – – – – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – – – – –
None – – – – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – – – – –
Punctate Nuclear – – – – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – – – – –
Vacuole Periphery – – – – – – – – – – – – – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 139.333 84.7143 110.7859 123.8296 121.6507 136.9114 128.4818 131.9351 146.2533 137.2782
Translational Efficiency 1.1081 1.4587 1.1225 1.3257 1.1169 1.2127 1.1492 0.9881 1.0937 1.0685

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization –
Gene Expression ✘
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Arp2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available