Standard name
Human Ortholog
Description Ceramide-activated, type 2A-related serine-threonine phosphatase; functions in G1/S transition of mitotic cycle; controls lifespan, mitochondrial function, cell cycle progression by regulating HXK2 phosphorylation; regulator of COPII coat dephosphorylation; required for ER to Golgi traffic; interacts with Hrr25p kinase; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization; similar to human PP6
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – – – – – – – – – – – 0 – 0 0 0 0 – – – – – –
Cell Periphery 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.92 – – – – – – – – – – – 0.87 – 0.95 0.85 0.88 0.85 0.9 0.75 0.84 0.86 0.73 0.53
Endoplasmic Reticulum 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0.15
Golgi 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0.05
Mitochondria 0.08 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0.07 0.08 0.06
Nucleus 0 – – – – – – – – – – – 0.09 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0.08 0 0 0 0.1
Vac/Vac Membrane 0 – – – – – – – – – – – 0 – 0 0.27 0.2 0.23 0 0 0.11 0.05 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 – – – – – – – – – – – 0 – 1 0 0 0 1 0 0 0 0 1
Bud Neck 0 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – – – – – – – – – – – 0 – 0 0 0 0 – – – – – –
Cell Periphery 0 – – – – – – – – – – – 0 – 1 24 14 21 0 0 0 0 0 1
Cytoplasm 68 – – – – – – – – – – – 20 – 41 1048 809 1058 88 18 5 31 54 36
Endoplasmic Reticulum 0 – – – – – – – – – – – 0 – 0 48 28 26 0 0 0 0 0 0
Endosome 1 – – – – – – – – – – – 0 – 1 27 13 8 2 0 0 0 2 10
Golgi 0 – – – – – – – – – – – 0 – 0 4 7 7 0 0 0 0 1 3
Mitochondria 6 – – – – – – – – – – – 0 – 1 5 11 22 1 0 0 2 5 4
Nucleus 0 – – – – – – – – – – – 2 – 1 9 1 3 0 0 0 0 0 0
Nuclear Periphery 1 – – – – – – – – – – – 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 1 – – – – – – – – – – – 0 – 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 – – – – – – – – – – – 0 – 0 2 0 0 0 0 0 0 1 2
SpindlePole 0 – – – – – – – – – – – 0 – 0 8 4 4 1 1 0 0 2 7
Vac/Vac Membrane 1 – – – – – – – – – – – 1 – 0 333 184 292 1 1 0 1 1 0
Unique Cell Count 74 23 43 1239 922 1247 99 25 7 37 75 70
Labelled Cell Count 78 23 46 1508 1071 1442 99 25 7 37 75 70


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 – – – – – – – – – – – 6.5 – 5.9 7.3 7.1 7.1 – 5.7 –
Std Deviation (1e-4) 0.6 – – – – – – – – – – – 0.6 – 0.9 1.0 1.1 1.0 – 0.9 –
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0144 0.0029 0.0124 0.0034 0.0314 0.0128 – – – – – – – – – – – –
Bud 0.0053 0.0058 0.0032 0.0003 0.003 0.0014 – – – – – – – – – – – –
Bud Neck 0.1142 0.0009 0.0015 0.0005 0.0011 0.0094 – – – – – – – – – – – –
Bud Periphery 0.0062 0.0025 0.0041 0.0002 0.0035 0.0009 – – – – – – – – – – – –
Bud Site 0.1032 0.0186 0.0208 0.0002 0.0031 0.0017 – – – – – – – – – – – –
Cell Periphery 0.0039 0.0004 0.0007 0 0.0003 0.0001 – – – – – – – – – – – –
Cytoplasm 0.097 0.5994 0.5579 0.6047 0.0245 0.5419 – – – – – – – – – – – –
Cytoplasmic Foci 0.0471 0.0181 0.0219 0.0102 0.0413 0.0392 – – – – – – – – – – – –
Eisosomes 0.0005 0.0001 0.0001 0.0001 0.0001 0 – – – – – – – – – – – –
Endoplasmic Reticulum 0.0192 0.0045 0.0051 0.0044 0.0013 0.0036 – – – – – – – – – – – –
Endosome 0.3033 0.0162 0.0187 0.013 0.1848 0.0332 – – – – – – – – – – – –
Golgi 0.0522 0.005 0.0071 0.0096 0.246 0.0064 – – – – – – – – – – – –
Lipid Particles 0.0118 0.0023 0.0017 0.0002 0.0121 0.0015 – – – – – – – – – – – –
Mitochondria 0.0953 0.0184 0.0066 0.0421 0.124 0.0015 – – – – – – – – – – – –
None 0.0079 0.267 0.2865 0.2684 0.3069 0.1461 – – – – – – – – – – – –
Nuclear Periphery 0.049 0.0037 0.0056 0.0095 0.0007 0.0091 – – – – – – – – – – – –
Nucleolus 0.0038 0.0013 0.0008 0.0002 0.0002 0.0015 – – – – – – – – – – – –
Nucleus 0.009 0.0174 0.0269 0.0252 0.0009 0.099 – – – – – – – – – – – –
Peroxisomes 0.0057 0.0017 0.004 0.0006 0.0055 0.0102 – – – – – – – – – – – –
Punctate Nuclear 0.0058 0.0068 0.0071 0.0052 0.0013 0.0762 – – – – – – – – – – – –
Vacuole 0.0369 0.0063 0.0063 0.0014 0.0042 0.0034 – – – – – – – – – – – –
Vacuole Periphery 0.0082 0.0009 0.0012 0.0006 0.0039 0.0008 – – – – – – – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 37.7232 34.7761 43.0089 41.7812 42.0319 36.5241 30.6336 30.564 45.047 47.0052
Translational Efficiency 1.3838 1.3123 1.1975 1.748 1.4327 1.3899 1.554 1.4496 1.2357 1.2563

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

No result is found for the queried gene(s). Please try another query.


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sit4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available