Standard name
Human Ortholog
Description Ribosomal protein 51 (rp51) of the small (40s) subunit; homologous to mammalian ribosomal protein S17, no bacterial homolog; RPS17A has a paralog, RPS17B, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.05 0.05 0 0.07 0.07 0.07 0 0.06 0 0 0.05 0.05 0.08 0 0.07 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.1 0 0 0.05 0 0 0 0.26 0.09 0.09 0.13 0.06 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.86 0.81 0.84 0.87 0.77 0.77 0.77 0.77 0.66 0.74 0.72 0.69 0.76 0.81 0.71 0.79 0.78 0.76 0.77 0.61 0.63 0.56 0.46 0.29
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0.05 0.06 0.07 0.08 0.17 0.13 0.27 0.27 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.1 0.12 0.1 0.08 0.13 0.09 0.07 0.1 0 0 0 0 0.11 0.13 0.15 0.13 0.18 0.22 0.18 0.29 0.3 0.35 0.45 0.55
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 1 0 1 0 1 0 0 3 0 0 0 0 0 0 3 0 2 1 2 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 3 7 5 1 6 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0
Cytoplasm 4 3 16 13 13 20 25 23 9 14 8 11 3 8 12 6 10 2 1 5 4 1 1 2
Endoplasmic Reticulum 0 1 0 1 0 0 0 0 0 0 0 0 0 1 0 2 1 2 0 0 1 0 1 2
Endosome 1 0 0 1 0 1 2 0 0 0 0 0 0 2 4 2 0 0 3 0 3 1 0 2
Golgi 0 0 2 1 0 3 0 2 0 0 0 0 0 0 3 2 2 1 1 3 1 2 1 1
Mitochondria 3 16 2 2 16 10 10 5 83 23 24 34 4 1 2 7 2 0 2 5 6 1 0 6
Nucleus 226 124 273 215 226 228 261 267 210 189 185 183 48 129 106 145 118 87 242 113 228 73 71 56
Nuclear Periphery 0 0 0 1 0 3 3 0 1 2 0 1 0 0 0 0 1 0 0 0 0 0 1 3
Nucleolus 12 5 1 1 14 17 25 28 53 33 69 70 2 1 4 0 0 0 1 0 1 0 1 6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 1 0 0 0
Vac/Vac Membrane 27 18 33 20 39 26 23 34 8 11 9 10 7 20 23 24 27 25 57 54 110 46 69 108
Unique Cell Count 263 154 324 248 294 296 338 345 318 254 257 264 63 159 150 183 152 115 316 186 365 132 155 196
Labelled Cell Count 273 167 327 255 309 308 350 362 372 277 296 318 64 164 154 189 162 117 316 186 365 132 155 196


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 14.0 9.8 14.0 13.3 10.2 11.9 11.6 13.0 10.6 11.1 11.6 10.5 14.1 14.8 13.6 12.4 16.4 17.6 15.5 16.6 16.6
Std Deviation (1e-4) 3.5 2.9 3.1 2.9 2.5 3.0 3.2 3.2 3.0 3.0 3.1 2.9 4.5 4.2 4.5 3.4 4.6 5.7 3.6 3.7 3.8
Intensity Change (Log2) – – – -0.07 -0.45 -0.23 -0.26 -0.11 -0.39 -0.33 -0.27 -0.41 0.01 0.08 -0.04 -0.17 0.23 0.33 0.15 0.25 0.25


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.2 -0.3 1.0 1.3 1.0 -1.4 0.3 -1.1 -0.4 0 0 1.3 -0.9 0.7 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 3.6 2.5 2.3 0 9.5 4.9 5.0 6.2 0 0 0 0 0 0
Nucleus 0.8 -2.3 -2.3 -2.3 -2.3 -5.3 -2.9 -3.6 -4.3 -1.6 -0.9 -3.4 -1.4 -1.8 -2.1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 3.6 4.0 4.7 5.0 7.5 6.4 9.8 9.7 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -0.9 1.2 -0.6 -1.6 -0.1 -4.0 -2.6 -3.1 -3.0 0.2 0.8 1.6 1.0 2.3 3.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 9.1418 9.6365 8.0559 8.9298 7.4369 9.1833 13.9773 14.6415 13.0753 13.3123 13.1902 13.4499 12.7154 12.1446 11.8848 11.8829 11.3399 11.8998
Actin 0.0373 0.0009 0.0073 0.0004 0.0169 0.0008 0.0017 0.0044 0.0006 0.0012 0.0056 0.0011 0.0143 0.0003 0.006 0.0014 0.0276 0.0082
Bud 0.0006 0.0004 0.0003 0.0003 0.0013 0.0007 0.0004 0.0005 0.0004 0.0007 0.0021 0.0005 0.0004 0.0002 0.001 0.0006 0.0025 0.0006
Bud Neck 0.0014 0.0004 0.0004 0.0004 0.002 0.0029 0.0003 0.0003 0.0004 0.0009 0.0042 0.0027 0.0008 0.0003 0.0009 0.0004 0.0051 0.0043
Bud Periphery 0.0012 0.001 0.0006 0.0004 0.0032 0.0031 0.0011 0.0011 0.0008 0.0017 0.0066 0.0022 0.0006 0.0005 0.0017 0.0014 0.0074 0.0029
Bud Site 0.0015 0.0003 0.0004 0.0002 0.0022 0.0004 0.0005 0.0005 0.0003 0.0002 0.0021 0.0004 0.0011 0.0003 0.0018 0.0003 0.0022 0.0004
Cell Periphery 0.0007 0.0006 0.0002 0.0003 0.0027 0.0013 0.0005 0.0003 0.0003 0.0004 0.0019 0.0005 0.0004 0.0002 0.0007 0.0005 0.0021 0.0008
Cytoplasm 0.0041 0.0011 0.0021 0.0012 0.0042 0.0009 0.0019 0.0011 0.0009 0.0011 0.0029 0.0014 0.0044 0.0012 0.0029 0.0008 0.0106 0.0008
Cytoplasmic Foci 0.0047 0.0001 0.0025 0 0.0159 0 0.0044 0.0002 0 0 0.0025 0.0001 0.0147 0.0001 0.0028 0 0.0163 0.0006
Eisosomes 0.0006 0 0.0001 0 0.0007 0 0.0001 0.0001 0 0 0.0002 0 0.0001 0 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.0031 0.0009 0.001 0.0001 0.0073 0.0011 0.0009 0.0021 0.0006 0.0004 0.0056 0.0027 0.003 0.0005 0.0028 0.0004 0.0062 0.0011
Endosome 0.0062 0.002 0.0074 0.0001 0.0244 0.0009 0.001 0.0034 0.0004 0.0005 0.0094 0.0019 0.014 0.0005 0.0111 0.0006 0.0125 0.0036
Golgi 0.0061 0.0002 0.002 0 0.0102 0 0.0008 0.0006 0 0 0.0048 0.0001 0.0051 0 0.0075 0.0001 0.0102 0.0008
Lipid Particles 0.0049 0.0002 0.0034 0 0.0152 0 0.0017 0.0006 0 0 0.0219 0.0003 0.0171 0.0001 0.0093 0.0001 0.0074 0.0005
Mitochondria 0.0166 0.0258 0.0267 0.0453 0.2023 0.0116 0.0311 0.058 0.0385 0.093 0.1159 0.0069 0.0106 0.011 0.0596 0.1063 0.1717 0.0118
None 0.0021 0.0001 0.001 0.0001 0.0042 0.0001 0.0163 0.0003 0.0001 0.0002 0.0005 0.0002 0.0026 0.0002 0.0004 0.0002 0.0153 0.0002
Nuclear Periphery 0.032 0.0256 0.0204 0.0064 0.0385 0.0262 0.0226 0.0282 0.0158 0.0197 0.0494 0.0223 0.0195 0.0196 0.018 0.0107 0.029 0.0184
Nucleolus 0.0156 0.0096 0.0111 0.0221 0.0265 0.0173 0.0147 0.008 0.0124 0.0059 0.0203 0.0198 0.013 0.0119 0.01 0.0159 0.0299 0.0276
Nucleus 0.8395 0.9173 0.9025 0.9184 0.5734 0.9157 0.8757 0.8809 0.9203 0.8658 0.7063 0.9202 0.8508 0.9451 0.8485 0.8481 0.5971 0.9036
Peroxisomes 0.0044 0.0001 0.001 0.0001 0.0048 0.0001 0.0102 0.0003 0.0001 0.0001 0.0162 0.0001 0.0095 0 0.001 0.0002 0.0027 0.0014
Punctate Nuclear 0.0025 0.0002 0.0012 0.0003 0.0049 0.0002 0.0011 0.0003 0.0002 0.0001 0.0007 0.0005 0.009 0.0012 0.0015 0.0002 0.0038 0.0015
Vacuole 0.0062 0.005 0.0039 0.0012 0.0131 0.008 0.0034 0.0027 0.0024 0.0022 0.0108 0.0068 0.005 0.0022 0.0065 0.0031 0.0165 0.0064
Vacuole Periphery 0.0088 0.0081 0.0043 0.0027 0.0261 0.0088 0.0098 0.0061 0.0054 0.0057 0.0102 0.0094 0.004 0.0047 0.0061 0.0086 0.0237 0.0044

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2636.3581 2896.73 3205.549 2635.6585 3017.8605 2997.13 2440.5317 2222.4637 2554.0328 2261.8598
Translational Efficiency 1.4912 1.3936 1.3381 1.6104 1.5386 1.3735 1.3928 1.8478 1.4055 1.6529

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘
Standard name
Human Ortholog
Description Ribosomal protein 51 (rp51) of the small (40s) subunit; homologous to mammalian ribosomal protein S17, no bacterial homolog; RPS17A has a paralog, RPS17B, that arose from the whole genome duplication
Localization
Cell Percentages nucleus (63%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-5

Rps17a

Rps17a


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rps17a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available